半岛bd体育手机客户端 介绍
基因名：
MARCHF4 半岛bd体育手机客户端 别名： MARCH-IV； MARCH4； RNF174； MARCHF4； membrane associated ring-CH-type finger 4； membrane associated ring-CH-type finger 4； E3 ubiquitin-protein ligase MARCHF4； E3 ubiquitin-protein ligase MARCH4； RING finger protein 174； RING-type E3 ubiquitin transferase MARCH4； RING-type E3 ubiquitin transferase MARCHF4； membrane associated ring finger 4； membrane-associated RING finger protein 4； membrane-associated RING-CH protein IV； membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase； 膜相关环指蛋白4； 背景信息：
MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
标签：His-tag |
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