蛋白质/抗原/多肽 >> 重组蛋白
重组锌指蛋白687
半岛bd体育手机客户端 介绍
基因名:
ZNF687 半岛bd体育手机客户端 别名: PDB6; ZNF687; zinc finger protein 687; zinc finger protein 687; 锌指蛋白687; 背景信息:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF687 (zinc finger protein 687) is a 1,237 amino acid nuclear protein that is involved in transcriptional regulation. A member of the Krüppel C2H2-type zinc-finger protein family, ZNF687 contains ten C2H2-type zinc fingers and exists as two alternatively spliced isoforms. The gene encoding ZNF687 maps to human chromosome 1, which comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
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