蛋白质/抗原/多肽 >> 重组蛋白
重组同源盒亮氨酸拉链蛋白HOMEZ
半岛bd体育手机客户端 介绍
基因名:
HOMEZ 半岛bd体育手机客户端 别名: KIAA1443; HOMEZ; homeobox and leucine zipper encoding; homeobox and leucine zipper encoding; homeobox and leucine zipper protein Homez; homeodomain leucine zipper-containing factor; 同源盒亮氨酸拉链蛋白HOMEZ; 背景信息:
Homeodomain-containing proteins function as transcription factors that typically switch on cascades of other genes. Usually homeodomain proteins act in the promoter region of their target genes as complexes with other transcription factors, leading to much higher target specificity than a single homeodomain protein. HOMEZ (Homeobox and leucine zipper protein) is a 525 amino acid nuclear protein that contains 3 atypical homeodomains, 2 leucine zipper-like motifs, proline and serine-rich motifs and an acidic domain. Within homeodomain 2, it contains a putative nuclear localization signal. HOMEZ shares significant sequence similarity with mouse ZHX1 and sequences that are homologous to HOMEZ are restricted to vertebrates. Likely functioning as a transcription regulator, HOMEZ is ubiquitously expressed with highest levels found in in ovary, testis, kidney, fetal lung and kidney.
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