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膜内蛋白酶4抗体
半岛bd体育手机客户端 介绍
靶标：
SPPL2B 半岛bd体育手机客户端 别名： IMP-4； IMP4； PSH4； PSL1； SPPL2B； signal peptide peptidase like 2B； signal peptide peptidase like 2B； signal peptide peptidase-like 2B； SPP-like 2B； intramembrane protease 4； presenilin homologous protein 4； presenilin-like protein 1； 膜内蛋白酶4； 背景信息：
SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.
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