半岛bd体育手机客户端 介绍
靶标:
HMCES 半岛bd体育手机客户端 别名: C3orf37; DC12; SRAPD1; HMCES; 5-hydroxymethylcytosine binding, ES cell specific; 5-hydroxymethylcytosine binding, ES cell specific; abasic site processing protein HMCES; 5-hydroxymethylcytosine (hmC) binding, ES cell-specific; ES cell-specific 5hmC-binding protein; SOS response associated peptidase domain containing 1; SRAP domain-containing protein 1; UPF0361 protein C3orf37; embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; peptidase HMCES; putative endonuclease HMCES; putative peptidase SRAPD1; 3号染色体开放阅读框37; 背景信息:
C3orf37, also known as DC12 or MGC111075, is a 354 amino acid protein encoded by a gene that maps to human chromosome 3q21.3. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
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