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PRICKLE4抗体
半岛bd体育手机客户端 介绍
靶标：
PRICKLE4 半岛bd体育手机客户端 别名： C6orf49； OBTP； OEBT； TOMM6； PRICKLE4； prickle planar cell polarity protein 4； prickle planar cell polarity protein 4； prickle-like protein 4； over-expressed breast tumor protein； overexpressed breast tumor protein； overexpressed breast tumour protein； prickle homolog 4； translocase of outer mitochondrial membrane 6 homolog； 背景信息：
PRICKLE4, also known as over-expressed breast tumor protein (OBTP), is a member of the LIM family of proteins. It possesses two LIM domains as well as a PET domain and is thought to localize to the nucleus. Its expression in multiple malignant tissue differentiations indicate that it may play a role in cancer differentiation. Two other members of the LIM family, PRICKLE1 and PRICKLE2, are thought to function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity, suggesting the PRICKLE4 may play a similar role.
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