靶标９�p style="text-indent: 2em;">A1CF

产品别名９�p style="text-indent: 2em;">ACF� ACF64� ACF65� APOBEC1CF� ASP� A1CF� APOBEC1 complementation factor� APOBEC1 complementation factor� APOBEC1 complementation factor� APOBEC-1 stimulating protein� apo-B RNA editing protein� apobec-1 complementation factor (ACF) (ASP)� 载脂蛋白B-mRNA编码蛋白�

背景信息９�div style="text-indent: 2em;">Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.