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溶质载体家族蛋白39成员A3抗体
半岛bd体育手机客户端 介绍
靶标:
SLC39A3 半岛bd体育手机客户端 别名: ZIP-3; ZIP3; SLC39A3; solute carrier family 39 member 3; solute carrier family 39 member 3; zinc transporter ZIP3; solute carrier family 39 (zinc transporter), member 3; zrt- and Irt-like protein 3; 溶质载体家族蛋白39成员A3; 背景信息:
SLC39A3 (solute carrier family 39, member 2), is a 314 amino acid acid multi-pass membrane protein that localizes to the cell membrane and belongs to the ZIP family of zinc transporters. Two isoforms of ZIP3 exist as a result of alternative splicing events. ZIP3 is involved in translocation of extracellular zinc into a variety of cell types. Tumorigenic prostate epithelial cells contain less intracellular zinc than non-tumorigenic prostate epithelial cells. Loss of the ability to maintain zinc accumulation may be caused by the decrease in the ZIP1 protein expression and the intracellular redistribution of ZIP3.
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