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神经元突触膜结合蛋白2抗体
半岛bd体育手机客户端 介绍
靶标:
RIMBP2 半岛bd体育手机客户端 别名: PPP1R133; RBP2; RIM-BP2; RIMBP2; RIMS binding protein 2; RIMS binding protein 2; RIMS-binding protein 2; RIM binding protein 2; protein phosphatase 1, regulatory subunit 133; 神经元突触膜结合蛋白2; 背景信息:
RIMS-binding proteins (RIM-BPs) serve as adaptors during vesicle fusion and release by forming links between synaptic-vesicle fusion apparatuses and calcium channels. Specifically, RIM-BP2 (RIMS binding protein 2), also known as RBP2, is a 1,052 amino acid protein that links L-type Ca++ CP Alpha1D, N-type Ca++ CP Alpha1B, Rim1 and Rim2 during synaptic transmission. RIM-BP2 contains three fibronectin type-III domains and three SH3 domains, which are used to mediate binding to a proline-rich motifs. Existing as three alternatively spliced isoforms, RIM-BP2 is encoded by a gene that maps to human chromosome 12q24.33 and mouse chromosome 5 G1.3.
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