试剂 半岛游戏平台官网入口网址 设备 原料
银牌会员第 1
访问量: 846945 网址:www.vuestras.com/show1000160 在线留言
半岛bd体育手机客户端 搜索
抗体 >> 其他抗体
ATP依赖的解旋酶SKIV2L2抗体
ATP依赖的解旋酶SKIV2L2抗体图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Anti-MTREX
Anti-Mtr4 exosome RNA helicase Antibody
半岛bd体育手机客户端 介绍
靶标:

MTREX


半岛bd体育手机客户端 别名:

Dob1; KIAA0052; Mtr4; SKIV2L2; fSAP118; MTREX; Mtr4 exosome RNA helicase; Mtr4 exosome RNA helicase; exosome RNA helicase MTR4; ATP-dependent RNA helicase DOB1; ATP-dependent RNA helicase SKIV2L2; ATP-dependent helicase SKIV2L2; Ski2 like RNA helicase 2; TRAMP-like complex helicase; functional spliceosome-associated protein 118; superkiller viralicidic activity 2-like 2; ATP依赖的解旋酶SKIV2L2;


背景信息:
Catalyzes the ATP-dependent unwinding of RNA duplexes with a single-stranded 3' RNA extension. Central subunit of many protein complexes, namely TRAMP-like, nuclear exosome targeting (NEXT and poly(A tail exosome targeting (PAXT. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. PAXT directs a subset of long and polyadenylated poly(A RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor ZCCHC8, which links to RNA-binding protein adapters. Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. May be involved in pre-mRNA splicing. In the context of NEXT complex can also in vitro unwind DNA:RNA heteroduplexes with a 3' poly (A RNA tracking strand. Can promote unwinding and degradation of structured RNA substrates when associated with the nuclear exosome and its cofactors. Can displace a DNA strand while translocating on RNA to ultimately degrade the RNA within a DNA/RNA heteroduplex. Plays a role in DNA damage response.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

相关半岛bd体育手机客户端
我要咨询 关闭
  • 姓名*
  • 电话*
  • 单位*
  • email
  • 留言内容*
  • 验证码*
  • 让更多商家关注
  • Baidu
    map