半岛bd体育手机客户端 介绍
靶标:
KAT6B 半岛bd体育手机客户端 别名: GTPTS; MORF; MOZ2; MYST4; ZC2HC6B; qkf; querkopf; KAT6B; lysine acetyltransferase 6B; lysine acetyltransferase 6B; histone acetyltransferase KAT6B; K(lysine) acetyltransferase 6B; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4; MOZ-related factor; MYST histone acetyltransferase (monocytic leukemia) 4; MYST-4; histone acetyltransferase MORF; histone acetyltransferase MOZ2; histone acetyltransferase MYST4; monocytic leukemia zinc finger protein-related factor; 组蛋白乙酰转移酶MORF; 背景信息:
The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012],
宿主:Rbt |
相关半岛bd体育手机客户端
|