蛋白质/抗原/多肽 >> 重组蛋白
重组睾丸酸性磷酸酶蛋白
半岛bd体育手机客户端 介绍
基因名:
ACP4 半岛bd体育手机客户端 别名: ACPT; AI1J; ACP4; acid phosphatase 4; acid phosphatase 4; testicular acid phosphatase; acid phosphatase, testicular; 睾丸酸性磷酸酶; 背景信息:
Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is upregulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. ACPT dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage. ACPT is predominantly expressed in testis but exhibits a lower level of expression in testicular cancer tissues than in normal tissues. ACPT has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
标签:His-tag |
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