蛋白质/抗原/多肽 >> 重组蛋白
重组HSD13蛋白
半岛bd体育手机客户端 介绍
基因名:
Fank1 半岛bd体育手机客户端 别名: 1700007B22Rik; AI850911; FANK1S; Fank1; fibronectin type 3 and ankyrin repeat domains 1; fibronectin type 3 and ankyrin repeat domains 1; fibronectin type 3 and ankyrin repeat domains 1 protein; GSG1; germ cell-specific 1; germ cell-specific gene 1 protein; HSD13蛋白; 背景信息:
FANK1 (fibronectin type III and ankyrin repeat domains 1), also known as HSD13, is a 345 amino acid nuclear and cytoplasmic testis-specific protein found primarily in pachytene spermatocytes and round spermatids. Containing six ANK repeats and a single fibronectin type-III domain, FANK1 undergoes alternative splicing events to form three isoforms. Possessing DNA binding activity, FANK1 is suggested to act as a transcription factor and may regulate gene expression during spermatogenesis. The gene encoding FANK1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.
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