蛋白质/抗原/多肽 >> 重组蛋白
重组16号染色体开放阅读框84蛋白
半岛bd体育手机客户端 介绍
基因名:
Ctu2 半岛bd体育手机客户端 别名: 2310061F22Rik; C16orf84; Ncs2; Ctu2; cytosolic thiouridylase subunit 2; cytosolic thiouridylase subunit 2; cytoplasmic tRNA 2-thiolation protein 2; cytosolic thiouridylase subunit 2 homolog; 16号染色体开放阅读框84; 背景信息:
CTU2 is a 515 amino acid cytoplasmic protein that plays a role in the 2-thiolation of mcm(5)S(2)U at wobble positions of tRNA. CTU2 forms a complex with CTU1 and Urm1, and may also form a separate heterodimer with CTU1 to ligate sulfur from thiocarboxylated Urm1 onto tRNA. Existing as three alternatively spliced isoforms, the gene encoding CTU2 maps to human chromosome 16q24.3. Chromosome 16 encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
标签:His-tag |
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