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蛋白质/抗原/多肽 >> 重组蛋白
重组高嗜酸性粒细胞综合症相关蛋白FIP1L1
重组高嗜酸性粒细胞综合症相关蛋白FIP1L1图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Recombinant Fip1l1
Recombinant FIP1 like 1 (S. cerevisiae) protein
半岛bd体育手机客户端 介绍
基因名:

Fip1l1


半岛bd体育手机客户端 别名:

1300019H17Rik; Rje; Fip1l1; FIP1 like 1 (S. cerevisiae); FIP1 like 1 (S. cerevisiae); pre-mRNA 3'-end-processing factor FIP1; FIP1-like 1 protein; 高嗜酸性粒细胞综合症相关蛋白FIP1L1;


背景信息:
The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA. This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail. FIP1L1 (FIP1-like 1), also known as Pre-mRNA 3'-end-processing factor FIP1, FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), is a 594 amino acid nuclear protein that is a component of the CPSF complex. Within the complex, FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition. Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage. There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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