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蛋白质/抗原/多肽 >> 重组蛋白
重组抑制蛋白结构域蛋白3
重组抑制蛋白结构域蛋白3图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Recombinant ARRDC3
Recombinant arrestin domain containing 3 protein
半岛bd体育手机客户端 介绍
基因名:

ARRDC3


半岛bd体育手机客户端 别名:

TLIMP; ARRDC3; arrestin domain containing 3; arrestin domain containing 3; arrestin domain-containing protein 3; TBP-2-like inducible membrane protein; alpha-arrestin 3; 抑制蛋白结构域蛋白3;


背景信息:
The arrestins are a family of proteins that are important for regulating signal transduction within cells. Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs). In response to a stimulus, GPCRs activate a heterotrimeric G protein. In order to turn off this response, or adapt to a constant stimulus, activated receptors need to be silenced. The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs). This phosphorylation specifically marks the activated receptor for arrestin binding. Once arrestin is bound to the receptor it is unable to signal further. Recent research continues to expand the known actions of arrestins, which can bind to other classes of receptors and can directly activate signaling pathways on their own. Different arrestins (visual arrestin (or Arrestin 1), beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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