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重组尤文氏瘤相关抗原1蛋白
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介绍 基因名: ETAA1 半岛bd体育手机客户端 别名: ETAA16; ETAA1; ETAA1 activator of ATR kinase; ETAA1 activator of ATR kinase; ewing's tumor-associated antigen 1; ETAA1, ATR kinase activator; Ewing tumor associated antigen 1; ewing's tumor-associated antigen 16; 尤文氏瘤相关抗原1; 背景信息: ETAA16 (Ewing's tumor-associated antigen 16), also known as ETAA1, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA16 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewing's family of tumour cell lines. The gene encoding ETAA16 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. 标签:His-tag |
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