蛋白质/抗原/多肽 >> 重组蛋白
重组锌指蛋白抑制NFκB蛋白
半岛bd体育手机客户端 介绍
基因名:
RNF216 半岛bd体育手机客户端 别名: CAHH; TRIAD3; U7I1; UBCE7IP1; ZIN; RNF216; ring finger protein 216; ring finger protein 216; E3 ubiquitin-protein ligase RNF216; RING-type E3 ubiquitin transferase RNF216; triad domain-containing protein 3; ubiquitin-conjugating enzyme 7-interacting protein 1; zinc finger protein inhibiting NF-kappa-B; 锌指蛋白抑制NFκB蛋白; 背景信息:
The TRIAD3 gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.
标签:His-tag |
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