蛋白质/抗原/多肽 >> 重组蛋白
重组钾离子通道四聚体结构域蛋白5
半岛bd体育手机客户端 介绍
基因名:
KCTD5 半岛bd体育手机客户端 别名: KCTD5; potassium channel tetramerization domain containing 5; potassium channel tetramerization domain containing 5; BTB/POZ domain-containing protein KCTD5; potassium channel tetramerisation domain containing 5; 钾离子通道四聚体结构域蛋白5; 背景信息:
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD5 (potassium channel tetramerisation domain containing 5) is a 234 amino acid protein that localizes predominantly in the cytoplasm but translocates to the nucleus upon interaction with REP proteins. Existing as a homopentamer and consisting of one BTB (POZ) domain, KCTD5 associates with GRASP55, CUL-3 and ubiquitinated proteins. Interaction with CUL-3 suggests KCTD5 functions as a substrate adapter protein in some E3 ligase complexes.
标签:His-tag |
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