半岛bd体育手机客户端 介绍
靶标：
Slc9b2 半岛bd体育手机客户端 别名： C80638； NHA2； NHE10； Nhedc2； nha-oc； nhaoc； Slc9b2； solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2； solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2； sodium/hydrogen exchanger 9B2； NHE domain-containing protein 2； Na(+)/H(+) exchanger NHA2； Na(+)/H(+) exchanger-like domain-containing protein 2； Na+/H+ exchanger domain containing 2； mitochondrial Na(+)/H(+) exchanger NHA2； mitochondrial sodium/hydrogen exchanger 9B2； mitochondrial sodium/hydrogen exchanger NHA2； soditlum/hydrogen exchanger-like domain-containing protein 2； sodium/hydrogen exchanger-like domain-containing protein 2； solute carrier family 9 subfamily B member 2； 线粒体钠/氢交换蛋白质2； 背景信息：
Na+ H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+ H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
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