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端粒调控因子2抗体
端粒调控因子2抗体图片
交货期: 1周
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交货期: 1周
半岛bd体育手机客户端 别名: 端锚聚合酶2(TNKS2)抗体
Anti-Tnks2
半岛bd体育手机客户端 介绍
靶标:

Tnks2


半岛bd体育手机客户端 别名:

5430432P15Rik; AA517131; AI662480; ARTD6; TNKS-2; Tank2; Tnks2; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; poly [ADP-ribose] polymerase tankyrase-2; ADP-ribosyltransferase diphtheria toxin-like 6; TRF1-interacting ankyrin-related ADP-ribose polymerase 2; protein poly-ADP-ribosyltransferase tankyrase-2; tankyrase II; tankyrase-2; tankyrase-like protein; tankyrase-related protein; 端粒调控因子2; 端锚聚合酶2(TNKS2);


背景信息:
catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,function:May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.,PTM:ADP-ribosylated (-auto).,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 15 ANK repeats.,subcellular location:Associated with the Golgi and with juxtanuclear SLC2A4/GLUT4-vesicles. Also found around the pericentriolar matrix of mitotic centromeres. During interphase, a small fraction of TNKS2 is found in the nucleus, associated with TRF1.,subunit:Oligomerizes and associates with TNKS. Interacts with the cytoplasmic domain of LNPEP/Otase in SLC2A4/GLUT4-vesicles. Binds to the N-terminus of Grb14 and TRF1 with its ankyrin repeat region.,tissue specificity:Highly expressed in placenta, skeletal muscle, liver, brain, kidney, heart, thymus, spinal cord, lung, peripheral blood leukocytes, pancreas, lymph nodes, spleen, prostate, testis, ovary, small intestine, colon, mammary gland, breast and breast carcinoma, and in common-type meningioma. Highly expressed in fetal liver, heart and brain.,

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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