半岛bd体育手机客户端 介绍
靶标：
Elovl7 半岛bd体育手机客户端 别名： 9130013K24Rik； AI840082； Elovl7； ELOVL family member 7, elongation of long chain fatty acids (yeast)； ELOVL family member 7, elongation of long chain fatty acids (yeast)； elongation of very long chain fatty acids protein 7； 3-keto acyl-CoA synthase Elovl7； ELOVL FA elongase 7； ELOVL fatty acid elongase 7； elongation of very long chain fatty acids-like 7； very long chain 3-ketoacyl-CoA synthase 7； very long chain 3-oxoacyl-CoA synthase 7； ELOVL7蛋白； 背景信息：
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.
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