半岛bd体育手机客户端 介绍
靶标:
MRPS18A 半岛bd体育手机客户端 别名: HumanS18b; MRP-S18-3; MRP-S18-a; MRPS18-3; S18bmt; S18mt-a; MRPS18A; mitochondrial ribosomal protein S18A; mitochondrial ribosomal protein S18A; 39S ribosomal protein S18a, mitochondrial; 28S ribosomal protein S18-3, mitochondrial; 28S ribosomal protein S18a, mitochondrial; 39S ribosomal protein S18-3, mitochondrial; mitochondrial large ribosomal subunit protein bS18a; mitochondrial large ribosomal subunit protein bS18m-A; mitochondrial large ribosomal subunit protein mL66; mitochondrial ribosomal protein S18-3; 线粒体核糖体蛋白S18A; 背景信息:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondria
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