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乳腺癌增强蛋白2抗体
半岛bd体育手机客户端 介绍
靶标：
SMG8 半岛bd体育手机客户端 别名： ALKUS； C17orf71； SMG8； SMG8 nonsense mediated mRNA decay factor； SMG8 nonsense mediated mRNA decay factor； nonsense-mediated mRNA decay factor SMG8； amplified in breast cancer gene 2 protein； protein SMG8； protein smg-8 homolog； smg-8 homolog, nonsense mediated mRNA decay factor； 乳腺癌增强蛋白2； 背景信息：
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
宿主：Rbt |
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