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黑色素瘤抗原样基因2抗体
半岛bd体育手机客户端 介绍
靶标:
Magel2 半岛bd体育手机客户端 别名: Mage-l2; NDNL1; nM15; ns7; Magel2; MAGE family member L2; MAGE family member L2; MAGE-like protein 2; melanoma antigen, family L, 2; melanoma antigen-like gene 2; necdin-like 1; protein nS7; 黑色素瘤抗原样基因2; 背景信息:
Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
宿主:Rbt |
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