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NAGPA蛋白抗体
半岛bd体育手机客户端 介绍
靶标:
Nagpa 半岛bd体育手机客户端 别名: AI596180; UCE; Nagpa; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase; alpha-GlcNAcase; mannose 6-phosphate-uncovering enzyme; phosphodiester alpha-GlcNAcase; NAGPA蛋白; 背景信息:
Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors inThe trans-Golgi network.This gene encodesThe enzyme that catalyzesThe second step inThe formation ofThe mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE,This enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties andThereby producesThe recognition marker.This reaction most likely occurs inThe trans-Golgi network.This enzyme functions as a homotetramer of two disulfide-linked homodimers. In addition to having an N-terminal signal peptide,The protein's C-terminus contains multiple signals for trafficking it between lysosomes,The plasma membrane, and trans-Golgi network. [provided by RefSeq, Jul 2008]
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