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含半胱氨酸和组氨酸丰富域蛋白1抗体
半岛bd体育手机客户端 介绍
靶标:
CHORDC1 半岛bd体育手机客户端 别名: CHP1; CHORDC1; cysteine and histidine rich domain containing 1; cysteine and histidine rich domain containing 1; cysteine and histidine-rich domain-containing protein 1; CHORD-containing protein 1; CHP-1; chord domain-containing protein 1; cysteine and histidine-rich domain (CHORD) containing 1; cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1; morgana; protein morgana; 含半胱氨酸和组氨酸丰富域蛋白1; 背景信息:
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis.
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