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AP3M1抗体
半岛bd体育手机客户端 介绍
靶标:
AP3M1 半岛bd体育手机客户端 别名: AP3M1; adaptor related protein complex 3 subunit mu 1; adaptor related protein complex 3 subunit mu 1; AP-3 complex subunit mu-1; AP-3 adapter complex mu3A subunit; adapter-related protein complex 3 mu-1 subunit; adaptor related protein complex 3 mu 1 subunit; clathrin adaptor complex AP3, mu-3A subunit; mu-adaptin 3A; mu3A-adaptin; 背景信息:
The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants.
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