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葡萄糖醛酸差向异构酶抗体
半岛bd体育手机客户端 介绍
靶标:
GLCE 半岛bd体育手机客户端 别名: HSEPI; GLCE; glucuronic acid epimerase; glucuronic acid epimerase; D-glucuronyl C5-epimerase; UDP-glucuronic acid epimerase; glucuronyl C5-epimerase; heparan sulfate C5-epimerase; heparan sulfate epimerase; heparin/heparan sulfate-glucuronic acid C5-epimerase; heparosan-N-sulfate-glucuronate 5-epimerase; 葡萄糖醛酸差向异构酶; 葡萄糖醛酸差向异构酶(GLCE); 背景信息:
Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773])
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