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ATP11B抗体
半岛bd体育手机客户端 介绍
靶标:
ATP11B 半岛bd体育手机客户端 别名: ATPIF; ATPIR; ATP11B; ATPase phospholipid transporting 11B (putative); ATPase phospholipid transporting 11B (putative); phospholipid-transporting ATPase IF; ATPase IR; ATPase, class VI, type 11B; P4-ATPase flippase complex alpha subunit ATP11B; probable phospholipid-transporting ATPase IF; 背景信息:
ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
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