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舌癌化疗耐药相关蛋白1抗体
半岛bd体育手机客户端 介绍
靶标:
FAM168A 半岛bd体育手机客户端 别名: KIAA0280; TCRP1; FAM168A; family with sequence similarity 168 member A; family with sequence similarity 168 member A; protein FAM168A; tongue cancer chemotherapy resistance-associated protein 1; 舌癌化疗耐药相关蛋白1; 背景信息:
FAM168A is a 244 amino acid protein that exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11, which makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and ??? thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
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