半岛bd体育手机客户端 介绍
靶标：
MGAT4B 半岛bd体育手机客户端 别名： GNT-IV； GNT-IVB； MGAT4B； alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B； alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B； alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B； N-acetylglucosaminyltransferase IVb； N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb； UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV； UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb； alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase； aminyltransferase； glcNAc-T IVb； mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme B； mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B； MGAT4B蛋白； 背景信息：
This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme A, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1, 4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.
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