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疣状表皮发育不良蛋白1抗体
半岛bd体育手机客户端 介绍
靶标:
TMC6 半岛bd体育手机客户端 别名: EV1; EVER1; EVIN1; LAK-4P; TNRC6C-AS1; lnc; TMC6; transmembrane channel like 6; transmembrane channel like 6; transmembrane channel-like protein 6; TNRC6C antisense RNA 1; epidermodysplasia verruciformis 1; epidermodysplasia verruciformis protein 1; expressed in activated T/LAK lymphocytes; protein LAK-4; 疣状表皮发育不良蛋白1; 背景信息:
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.
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