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160kDa内含子结合蛋白抗体
半岛bd体育手机客户端 介绍
靶标:
AQR 半岛bd体育手机客户端 别名: IBP160; fSAP164; AQR; aquarius intron-binding spliceosomal factor; aquarius intron-binding spliceosomal factor; RNA helicase aquarius; aquarius homolog; functional spliceosome-associated protein 164; intron-binding protein aquarius; intron-binding protein of 160 kDa; 160kDa内含子结合蛋白; 背景信息:
Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint during the late stages of splicing. Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro.
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