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整合素样金属蛋白酶与凝血酶样2蛋白抗体
半岛bd体育手机客户端 介绍
靶标:
ADAMTSL2 半岛bd体育手机客户端 别名: ADAMTSL-2; GPHYSD1; ADAMTSL2; ADAMTS like 2; ADAMTS like 2; ADAMTS-like protein 2; 整合素样金属蛋白酶与凝血酶样2蛋白; 背景信息:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009],
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