半岛bd体育手机客户端 介绍
靶标：
TAF2 半岛bd体育手机客户端 别名： CIF150； MRT40； TAF2B； TAFII150； TAF2； TATA-box binding protein associated factor 2； TATA-box binding protein associated factor 2； transcription initiation factor TFIID subunit 2； 150 kDa cofactor of initiator function； RNA polymerase II TBP-associated factor subunit B； TAF(II)150； TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa； TATA box binding protein (TBP)-associated factor, RNA polymerase II, B, 150kD； TBP-associated factor 150 kDa； cofactor of initiator function, 150kD subunit； transcription initiation factor TFIID 150 kDa subunit； TATA框结合蛋白关联因子2(TAF2)； 背景信息：
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream
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