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ATP依赖RNA解旋酶Supv3L1抗体
半岛bd体育手机客户端 介绍
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SUPV3L1 半岛bd体育手机客户端 别名: SUV3; SUPV3L1; Suv3 like RNA helicase; Suv3 like RNA helicase; ATP-dependent RNA helicase SUPV3L1, mitochondrial; SUV3-like helicase; SUV3-like protein 1; suppressor of var1, 3-like 1; suppressor of var1, 3-like 1(SUV3); ATP依赖RNA解旋酶Supv3L1; 背景信息:
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
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