半岛bd体育手机客户端 介绍
靶标：
KCNQ3 半岛bd体育手机客户端 别名： BFNC2； EBN2； KV7.3； KCNQ3； potassium voltage-gated channel subfamily Q member 3； potassium voltage-gated channel subfamily Q member 3； potassium voltage-gated channel subfamily KQT member 3； potassium channel subunit alpha KvLQT3； potassium channel, voltage gated KQT-like subfamily Q, member 3； potassium channel, voltage-gated, subfamily Q, member 3； potassium voltage-gated channel, KQT-like subfamily, member 3； voltage-gated potassium channel subunit Kv7.3； 电压门控钾通道亚基Kv7.3； 背景信息：
This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants.
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