半岛bd体育手机客户端 介绍
靶标:
HLA-DQA2 半岛bd体育手机客户端 别名: DC-alpha; DQA1; DX-ALPHA; HLA-DCA; HLA-DXA; HLADQA2; HLA-DQA2; major histocompatibility complex, class II, DQ alpha 2; major histocompatibility complex, class II, DQ alpha 2; HLA class II histocompatibility antigen, DQ alpha 2 chain; DC-1 alpha chain; DX alpha chain; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; MHC class I antigen; MHC class II DQA1; MHC class II DQA2; MHC class II antigen; 背景信息:
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.
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