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重组跨膜蛋白KREMEN2
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介绍 基因名: Kremen2 半岛bd体育手机客户端 别名: 2900054E04Rik; Krm2; Kremen2; kringle containing transmembrane protein 2; kringle containing transmembrane protein 2; kremen protein 2; dickkopf receptor 2; kringle domain-containing transmembrane protein 2; kringle-containing protein marking the eye and the nose; 跨膜蛋白KREMEN2; 背景信息: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] 标签:His-tag |
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