蛋白质/抗原/多肽 >> 重组蛋白
重组锌指蛋白340
半岛bd体育手机客户端 介绍
基因名：
Zbtb46 半岛bd体育手机客户端 别名： 2610019F01Rik； 4933406L05Rik； BZEL； Btbd4； Zbtb46； zinc finger and BTB domain containing 46； zinc finger and BTB domain containing 46； zinc finger and BTB domain-containing protein 46； BTB (POZ) domain containing 4； BTB-ZF protein expressed in effector lymphocytes； BTB/POZ domain-containing protein 4； 锌指蛋白340； 背景信息：
BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
标签：His-tag |
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