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重组乳腺癌基因删除蛋白2
半岛bd体育手机客户端
介绍 基因名: RHOBTB2 半岛bd体育手机客户端 别名: DBC2; DEE64; EIEE64; p83; RHOBTB2; Rho related BTB domain containing 2; Rho related BTB domain containing 2; rho-related BTB domain-containing protein 2; deleted in breast cancer 2 gene protein; 乳腺癌基因删除蛋白2; 背景信息: DBC2 is a member of the recently identified RhoBTB family, which is part of the Rho GTPase family. DBC2 has been implicated as a tumor suppressor in breast and lung cancer. Studies have shown that DBC2 binds to the ubiquitin ligase scaffold Cul3, and that Cul3 regulates DBC2 protein levels by ubiquitinating DBC2 directly, leading to its degradation by the proteasome. 标签:His-tag |
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