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重组LRBA蛋白
半岛bd体育手机客户端
介绍 基因名: LRBA 半岛bd体育手机客户端 别名: BGL; CDC4L; CVID8; LAB300; LBA; LRBA; LPS responsive beige-like anchor protein; LPS responsive beige-like anchor protein; lipopolysaccharide-responsive and beige-like anchor protein; CDC4-like protein; LPS-responsive vesicle trafficking, beach and anchor containing; vesicle trafficking, beach and anchor containing; LRBA蛋白; 背景信息: The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012] 标签:His-tag |
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