凋亡加强结构域蛋白15样蛋白抗体

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凋亡加强结构域蛋白15样蛋白抗体

交货期: 1周
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交货期:	1周
半岛bd体育手机客户端别名:	Anti-NLRC3 Anti-NLR family CARD domain containing 3 Antibody

半岛bd体育手机客户端介绍

靶标：

NLRC3

半岛bd体育手机客户端别名：

CLR16.2； NOD3； NLRC3； NLR family CARD domain containing 3； NLR family CARD domain containing 3； NLR family CARD domain-containing protein 3； CARD15-like protein； NACHT, LRR and CARD domains-containing protein 3； NOD-like receptor C3； caterpiller protein 16.2； nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3；凋亡加强结构域蛋白15样蛋白；

背景信息：

NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-κB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。