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磷脂酰肌醇PREX2抗体
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介绍 靶标: PREX2 半岛bd体育手机客户端 别名: DEP.2; DEPDC2; P-REX2; PPP1R129; PREX2; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; DEP domain-containing protein 2; PtdIns(3,4,5)-dependent Rac exchanger 2; protein phosphatase 1, regulatory subunit 129; 磷脂酰肌醇PREX2; 背景信息: PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. 宿主:Rbt |
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