半岛bd体育手机客户端
介绍 靶标: Spdya 半岛bd体育手机客户端 别名: 4921517J08Rik; 4930548B21Rik; GS4; MLZ-465; Spdy1; Spdya; speedy/RINGO cell cycle regulator family, member A; speedy/RINGO cell cycle regulator family, member A; speedy protein A; RINGO A; mSpy/Ringo A; protein expressed in male leptotene and zygotene spermatocytes 465; rapid inducer of G2/M progression in oocytes A; speedy A; speedy A1; speedy A2; speedy homolog 1; speedy homolog A; speedy-1; spermatogenesis related protein Gs4; spy1; 快速蛋白A; 背景信息: Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Mediates cell survival during the DNA damage process through activation of CDK2. 宿主:Rbt |
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