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EFHA1蛋白抗体
半岛bd体育手机客户端
介绍 靶标: Micu2 半岛bd体育手机客户端 别名: 1110008L20Rik; 4833427E09Rik; AU041871; Efha1; Smhs2; Micu2; mitochondrial calcium uptake 2; mitochondrial calcium uptake 2; calcium uptake protein 2, mitochondrial; EF hand domain family A1; EF-hand domain-containing family member A1; EFHA1蛋白; 背景信息: Key regulator of mitochondrial calcium uniporter (MCU required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering. 宿主:Rbt |
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