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SCK蛋白抗体
半岛bd体育手机客户端
介绍 靶标： SHC2 半岛bd体育手机客户端 别名： SCK； SHCB； SLI； SHC2； SHC adaptor protein 2； SHC adaptor protein 2； SHC-transforming protein 2； SH2 domain protein C2； SHC (Src homology 2 domain containing) transforming protein 2； SHC-transforming protein B； neuronal Shc adaptor homolog； protein Sck； src homology 2 domain-containing-transforming protein C2； SCK蛋白； SHC-转化蛋白2(SHC2)； 背景信息： domain:The PID domain mediates binding to the TrkA receptor.,function:Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.,miscellaneous:PubMed:15057824 has shown that SHC2 is poorly phosphorylated by the Trk receptors, in opposite to PubMed:12006576.,PTM:Phosphorylated on tyrosines by the Trk receptors.,similarity:Contains 1 PID domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with the Trk receptors in a phosphotyrosine-dependent manner and MEGF12. Once activated, binds to GRB2.,tissue specificity:Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus., 宿主：Rbt |
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