Zotepine 是一种抗精神病药物,是 5-HT2A、5-HT2C、组胺 H1、α1-肾上腺素能受体和多巴胺 D2 受体的有效拮抗剂,Kd 值分别为 2.6 nM、3.2 nM、3.3 nM、7.3 nM 和 8 nM。
Cas No. | 26615-21-4 |
别名 | 佐替平 |
化学名 | 2-((8-chlorodibenzo[b,f]thiepin-10-yl)oxy)-N,N-dimethylethanamine |
Canonical SMILES | ClC1=CC=C2SC3=CC=CC=C3C=C(C2=C1)OCCN(C)C |
分子式 | C18H18ClNOS |
分子量 | 331.86 |
溶解度 | DMF: 10 mg/ml,DMSO: 2 mg/ml,Ethanol: 10 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |