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N-heptanoyl-L-Homoserine lactone
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-heptanoyl-L-Homoserine lactone图片
CAS NO:177158-20-2
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

半岛bd体育手机客户端 介绍
N-庚酰基-L-高丝氨酸内酯是N-酰基-高丝氨酸内酯家族的成员。
Cas No.177158-20-2
别名C7-HSL
化学名N-[(3S)-tetrahydro-2-oxo-3-furanyl]-heptanamide
Canonical SMILESCCCCCCC(=O)N[C@H]1CCOC1=O
分子式C11H19NO3
分子量213.3
溶解度30 mg/ml in DMSO, 30 mg/ml in DMF, 20 mg/ml in Ethanol
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is involved in a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-heptanoyl-L-Homoserine lactone (C7-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. [1] [2] The diverse applications of this molecule include regulation of virulence, infection prevention, and septicemia in fish. [3]

Reference:
[1]. Lithgow, J.K., Wilkinson, A., Hardman, A., et al. The regulatory locus cinRI in Rhizobium leguminosarum controls a network of quorum-sensing loci. Molecular Microbiology 37(1), 81-97 (2000).
[2]. Barnard, A.M.L., and Salmond, G.P.C. Quorum sensing: The complexities of chemical communication between bacteria. Complexus 5(2), 87-101 (2004).
[3]. Morohoshi, T., Inaba, T., Kato, N., et al. Identification of quorum-sensing signal molecules and the LuxRI homologs in fish pathogen edwardsiella tarda. Journal of Bioscience and Bioengineering 98(4), 274-281 (2004).

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